Clinical Example: Radical Sympathectomy

Severe peripheral vascular insufficiency associated with connective tissue disease is usually due to a combination of vasospastic (Raynaud's) and fixed (proliferative vessel wall changes) factors. Periarterial sympathectomy is one approach to this problem. This technique involves stripping the adventitia from the affected vessels, which both removes the sympathetic nerve innervation (preventing nerve mediated vessel constriction) and externally decompresses the vessels, allowing dilation of the vessel lumen. The original description by Flatt involved stripping a small length of the vessels at the level of the common digital artery bifurcation. This was later expanded by O'Brien and others to include the entire vascular tree, from forearm to fingertips - referred to as a radical periarterial sympathectomy. This patient was treated on O'Brien's service and shows some of the difficulties associated with this procedure.

 
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This young gentleman with mixed connective tissue disease has intolerably painful fingers and persistent gangrene of the fingertips.
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Arteriogram shows palmar arterial vessels to be patent, but diffusely narrowed.
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Incision plan for the vessel exploration.
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All vessels stripped.
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Postoperatively, the patient experienced significant pain relief, although had progressive gangrene of the fingertips.
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These were allowed to autoamputate. Pain relief persisted, although stiffness persisted.
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Unusual scar hypertrophy.
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